Does Dymo 450 label printer work with Paypal shipping?

I’m looking into buying a label printer and my OS is vista. I see they have an option for the old 400 Dymo in paypal shipping, but that one uis being discontinued and will be replaced with the 450 which works with vista. Can I just select 400 and use the 450? Does anyone have a 450 and using paypal shipping???? Your help is greatly appreciated!